Any logs on the system? Might be a time for a 3300 reboot however if a call to the users reestablishes presence I am not sure a 3300 reboot will help. Any software upgrades recently, any network changes. Think the presence requires the 3300 to establish "monitors" in the 3300 for the extensions on the system. There is a maintenance command to see how many monitors are in use on the 3300. Can you see if you are running out? There is a limitation on how many monitors the 3300 can have. Even though you only have 90 UCA clients the 3300 opens the monitors against all the most of the physical sets. We ran into an issue on a MCD 4 site where we opened too many monitors and got all kinds of alarms. Required upgrade to MCD 5 which can open double the number of monitors.