While I have no experience with this particular need, I am assuming that a higher end BlueTooth device would be the answer. BlueTooth is the only way I know how to go wireless with a PC. If I pair a BlueTooth headset to my smartphone, I can answer it that way. So why not pair it with a PC.
The only way to validate it would be to take a $30 BT ear piece lying around, pair it to the PC, and then attempt to answer the call.
This is a pretty cool idea. The sets are cheaper than the plantronics DECT sets too, though there may be a reason for that.