That depends on a few variables. You can make voice calls both internally and over the PSTN with no problem. However, if you want to share presentations or video, you're a bit more limited. You can natively connect with video between other UC360's in your organization. In addition, you can use the built-in apps (WebEx, Join.Me, MiCollab, etc.) to share presentations with any other external parties able to connect to those apps. For external videoconferencing, you need to connect to a 3rd party service, like Vidyo.
Personally, I'm hoping an upcoming release includes Google Hangouts integration, but I haven't heard anything on if that's in the roadmap for the product.