There isn't a way to do this in call director, as the system would only be listening for one DTMF tone, so it would hear the 1, and then put you through to option 1, ignoring the 0.
I would be creating sub menus and using them if there were too many options. There is usually some way that you can logically group a few of the options together to make a sub menu from there.
I think Ralph was thinking that you were doing this on embedded VM, as then you would have to create mailboxes for the options, but from your question you are using call director in Nupoint?